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Mater Sci Eng C Mater Biol Appl. 2012 Aug 1;32(6):1486-9. doi: 10.1016/j.msec.2012.04.029. Epub 2012 Apr 24.

Effect of iron-doped multi-walled carbon nanotubes on lipid model and cellular plasma membranes.

Author information

1
Kyiv National Taras Shevchenko University, ESC "Institute of Biology", Volodymyrska Str., 64, 01601 Kyiv, Ukraine.
2
Institute of Cell Biology, NAS of Ukraine, Drahomanov Str. 14/16, 79005 Lviv, Ukraine.
3
Institute of Physics of NAS of Ukraine, Nauky Avenue. 46, 680028 Kyiv, Ukraine.
4
Technical University of Ilmenau, Institut of Chemistry and Biotechnology, Weimarer Str. 25, 98693 Ilmenau, Germany.

Abstract

The aim of the present work was the study of the interaction of multi-walled carbon nanotubes filled with iron (Fe-MWCNTs) with bimolecular lipid model membrane (BLM) and cellular plasma membrane (PM). The findings demonstrate that the Fe-MWCNTs adsorb on the BLM surface with possible partial build up in the hydrophobic area of fatty acid residues of lipids and increase its specific conductivity and capacity. Furthermore, upon interaction with the PM, the Fe-MWCNTs form channels which allow the flow of water to the cells and the externalization of phosphatidylserine from the inner to the outer PM leaflet.

PMID:
24364949
DOI:
10.1016/j.msec.2012.04.029
[Indexed for MEDLINE]

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