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Nat Cell Biol. 2014 Jan;16(1):66-76. doi: 10.1038/ncb2893. Epub 2013 Dec 22.

A secreted peptide acts on BIN2-mediated phosphorylation of ARFs to potentiate auxin response during lateral root development.

Author information

1
1] Department of Life Sciences, Pohang University of Science and Technology, Pohang 790-784, Korea [2].
2
School of Interdisciplinary Bioscience and Bioengineering, Pohang University of Science and Technology, Pohang 790-784, Korea.
3
1] Division of Plant and Crop Sciences, School of Biosciences University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK [2] Centre for Plant Integrative Biology, University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK.
4
Division of Plant and Crop Sciences, School of Biosciences University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK.
5
1] Integrative Plant Biology Division, Department of Plant Systems Biology, VIB, Technologiepark 927, Ghent 9052, Belgium [2] Department of Plant Biotechnology and Bioinformatics, Ghent University, Technologiepark 927, Ghent 9052, Belgium.
6
Department of Life Sciences, Pohang University of Science and Technology, Pohang 790-784, Korea.
7
1] Division of Plant and Crop Sciences, School of Biosciences University of Nottingham, Sutton Bonington Campus, Loughborough LE12 5RD, UK [2] Integrative Plant Biology Division, Department of Plant Systems Biology, VIB, Technologiepark 927, Ghent 9052, Belgium [3] Department of Plant Biotechnology and Bioinformatics, Ghent University, Technologiepark 927, Ghent 9052, Belgium.

Abstract

The phytohormone auxin is a key developmental signal in plants. So far, only auxin perception has been described to trigger the release of transcription factors termed Auxin Response Factors (ARFs) from their auxin/indole-3-acetic acid (AUX/IAA) repressor proteins. Here, we show that phosphorylation of ARF7 and ARF19 by BRASSINOSTEROID-insensitive2 (BIN2) can also potentiate auxin signalling output during lateral root organogenesis. BIN2-mediated phosphorylation of ARF7 and ARF19 suppresses their interaction with AUX/IAAs, and subsequently enhances the transcriptional activity to their target genes lateral organ boundaries-domain16 (LBD16) and LBD29. In this context, BIN2 is under the control of the Tracheary element differentiation inhibitory factor (TDIF)-TDIF receptor (TDR) module. TDIF-initiated TDR signalling directly acts on BIN2-mediated ARF phosphorylation, leading to the regulation of auxin signalling during lateral root development. In summary, this study delineates a TDIF-TDR-BIN2 signalling cascade that controls regulation of ARF and AUX/IAA interaction independent of auxin perception during lateral root development.

Comment in

PMID:
24362628
DOI:
10.1038/ncb2893
[Indexed for MEDLINE]

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