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Nature. 1987 Mar 26-Apr 1;326(6111):358-63.

Three-dimensional structure of a complex of antibody with influenza virus neuraminidase.

Abstract

The structure of a complex between influenza virus neuraminidase and an antibody displays features inconsistent with the inflexible 'lock and key' model of antigen-antibody binding. The structure of the antigen changes on binding, and that of the antibody may also change; the interaction therefore has some of the character of a handshake.

PMID:
2436051
DOI:
10.1038/326358a0
[Indexed for MEDLINE]

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