A new megastigmane glycoside from the aerial parts of Cirsium setosum

Chin J Nat Med. 2013 Sep;11(5):534-7. doi: 10.1016/S1875-5364(13)60097-7.

Abstract

Aim: To study the chemical constituents of the aerial parts of Cirsium setosum (Willd.) MB..

Methods: The chemical constituents were isolated and purified by various chromatographic techniques. Their structures were determined on the basis of physical properties and spectroscopic data.

Results: A new megastigmane glycoside and six known compounds were obtained and identified as (7E, 9R)-9-hydroxy-5, 7-megastigmadien-4-one-9-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyanoside (1), (6R, 7E, 9R)-9-hydroxy-4, 7-megastigmadien-3-one-9-O-α-L-arabinopyranosyl-(1→6)-β-D-glucopyranoside (2), urolignoside (3), 4, 9, 9'-trihydroxy-3, 3'-dimethoxy-8-O-4$\prime $-neolignan-7-O-β-D-glucopyranoside (4), citroside A (5), salidrosidin (6), and adenosine (7).

Conclusion: Compound 1 is a new megastigmane glycoside, named as Xiaojiglycoside A.

Keywords: Cirsium setosum; Compositae; Megastigmane glycoside; Xiaojiglycoside A.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Cirsium / chemistry*
  • Cyclohexanones / chemistry*
  • Cyclohexanones / isolation & purification
  • Drugs, Chinese Herbal / chemistry*
  • Drugs, Chinese Herbal / isolation & purification
  • Glucosides / chemistry*
  • Glucosides / isolation & purification
  • Molecular Structure
  • Norisoprenoids / chemistry*
  • Norisoprenoids / isolation & purification
  • Plant Components, Aerial / chemistry*

Substances

  • Cyclohexanones
  • Drugs, Chinese Herbal
  • Glucosides
  • Norisoprenoids
  • megastigmane