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Nat Prod Rep. 2014 Jan 17;31(2):154-9. doi: 10.1039/c3np70081j.

A natural prodrug activation mechanism in the biosynthesis of nonribosomal peptides.

Author information

1
Merck Stiftungsprofessur für Molekulare Biotechnologie, Fachbereich Biowissenschaften, Goethe Universität Frankfurt, Max-von-Laue-Str. 9, Biozentrum/Campus Riedberg, 60438 Frankfurt am Main, Germany. h.bode@bio.uni-frankfurt.de.

Abstract

Highlight describes the recently discovered prodrug activation mechanism found in the biosynthesis of nonribosomally produced peptides and peptide/polyketide hybrids as well as related mechanisms.

PMID:
24356302
DOI:
10.1039/c3np70081j
[Indexed for MEDLINE]

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