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Chem Commun (Camb). 2014 Feb 11;50(12):1423-5. doi: 10.1039/c3cc47215a.

Creation of artificial cellulosomes on DNA scaffolds by zinc finger protein-guided assembly for efficient cellulose hydrolysis.

Author information

1
Department of Chemical and Biomolecular Engineering, University of Delaware, Newark, Delaware 19716, USA. wilfred@udel.edu.

Abstract

For the first time, artificial cellulosome structures were created on DNA scaffolds based on zinc finger protein (ZFP)-guided assembly. These resulting two-component cellulosome structures exhibited enhancement in cellulose hydrolysis compared to the non-complexed mixture depending on the number of CBMs and cellulases assembled.

PMID:
24350330
DOI:
10.1039/c3cc47215a
[Indexed for MEDLINE]

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