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Oncol Lett. 2014 Jan;7(1):199-202. Epub 2013 Nov 8.

Primary yolk sac tumour of the urinary bladder: A case report and review of the literature.

Author information

1
Department of Clinical Oncology, Tuen Mun Hospital, Tuen Mun, Hong Kong SAR, P.R. China.
2
Department of Pathology, Tuen Mun Hospital, Tuen Mun, Hong Kong SAR, P.R. China.
3
Department of Surgery, Division of Urology, Tuen Mun Hospital, Tuen Mun, Hong Kong SAR, P.R. China.

Abstract

We present a case of rare primary yolk sac tumour of the urinary bladder in adulthood. A 31-year-old female patient presented with a history of chronic ketamine abuse, which has not previously been shown to be associated with malignancy development. The final diagnosis was established only after radical cystectomy. A computed tomography (CT) scan showed paraaortic lymph node metastasis. The patient was treated with systemic chemotherapy. A review of the literature revealed that surgical excision and cisplatin-based chemotherapy remain to be the standard of care for extragonadal yolk sac tumours.

KEYWORDS:

ketamine abuse; urinary bladder; yolk sac tumour

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