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Obes Res Clin Pract. 2009 Aug;3(3):I-IV. doi: 10.1016/j.orcp.2009.04.005.

Licorice flavonoid oil reduces total body fat and visceral fat in overweight subjects: A randomized, double-blind, placebo-controlled study.

Author information

1
Depertment of Clinical Nutrition, Kiryu University, Midori-City, Gumma, Japan.
2
Depertment of Clinical Nutrition, Kiryu University, Midori-City, Gumma, Japan. Electronic address:ishuji@kiryu-u.ac.jp.

Abstract

SUMMARY:

OBJECTIVES:

To evaluate effects of licorice flavonoid oil (LFO) on total body fat and visceral fat together with body weight, body mass index (BMI) and safety parameters in overweight subjects.

METHODS:

In this randomized, double-blind, placebo-controlled study, moderately overweight participants (56 males, 28 females, BMI 24-30 kg/m(2)) were assigned to four groups receiving a daily dose of either 0 (placebo), 300, 600, or 900 mg of LFO. Total body fat mass was measured by dual-energy X-ray absorptiometry (DXA) and visceral fat area by abdominal computed tomography (CT) scan at baseline and after 8 weeks of LFO ingestion. Body weight, BMI, and blood samples were examined at baseline and after 4 and 8 weeks of LFO ingestion.

RESULTS:

Although caloric intake was similar in all four groups, total body fat mass decreased significantly in the three LFO groups after 8 weeks of ingestion. LFO (900 mg/day) resulted in significant decreases from baseline levels in visceral fat area, body weight, BMI, and LDL-cholesterol. No significant adverse effects were observed.

PMID:
24345587
DOI:
10.1016/j.orcp.2009.04.005

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