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J Pediatr. 2014 Mar;164(3):658-60. doi: 10.1016/j.jpeds.2013.10.090. Epub 2013 Dec 15.

How are childhood thyroid nodules discovered: opportunities for improving early detection.

Author information

1
Thyroid Program of the Division of Endocrinology, Children's Hospital Boston, Boston, MA.
2
Department of Radiology, Brigham and Women's Hospital, Boston, MA.
3
Thyroid Program of the Division of Endocrinology, Children's Hospital Boston, Boston, MA; Thyroid Section of the Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston, MA.
4
Thyroid Section of the Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston, MA; Dana Farber Cancer Institute, Boston, MA.
5
Department of Pathology, Brigham and Women's Hospital, Boston, MA.
6
Department of Surgery, Children's Hospital Boston, Boston, MA.
7
Department of Radiology, Children's Hospital Boston, Boston, MA.
8
Clinical Research Program, Children's Hospital Boston, Boston, MA; Dana Farber Cancer Institute, Boston, MA.
9
Clinical Research Program, Children's Hospital Boston, Boston, MA.
10
Department of Pathology, Children's Hospital Boston, Boston, MA.
11
Department of Surgery, Brigham and Women's Hospital, Boston, MA.
12
Thyroid Program of the Division of Endocrinology, Children's Hospital Boston, Boston, MA; Thyroid Section of the Division of Endocrinology, Diabetes, and Hypertension, Brigham and Women's Hospital, Boston, MA; Dana Farber Cancer Institute, Boston, MA. Electronic address: stephen.huang@childrens.harvard.edu.

Abstract

In a retrospective analysis of childhood thyroid nodules, 18% were radiographic incidentalomas and 41% were discovered by a clinician's palpation; 40% were discovered by patients' families. The latter group had the largest nodules and highest rates of thyroid cancer metastasis, suggesting opportunities for earlier detection through annual well-child visits.

PMID:
24345455
PMCID:
PMC4185424
DOI:
10.1016/j.jpeds.2013.10.090
[Indexed for MEDLINE]
Free PMC Article

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