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Arch Virol. 2014 Jun;159(6):1467-73. doi: 10.1007/s00705-013-1950-x. Epub 2013 Dec 15.

Circulation of classical swine influenza virus in Europe between the wars?

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Department of Virology and Antiviral Therapy, Jena University Hospital, Friedrich Schiller University, Hans-Knoell-Str. 2, 07745, Jena, Germany.


The complete genomes of two swine influenza viruses from England were sequenced. Phylogenetic analysis revealed classical swine H1N1 viruses, one of which, A/swine/London, is closely related to virus strains of the early 1930s. Both strains are also antigenically related to A/swine/Iowa/15/1930, the strain originally isolated by Richard Shope. The source of A/swine/London is unknown, but its relationship to early classical swine influenza viruses suggests that the emergence of these viruses in Europe has to be antedated by 15-20 years.

[Indexed for MEDLINE]

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