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Bioinformatics. 2014 Feb 15;30(4):576-7. doi: 10.1093/bioinformatics/btt712. Epub 2013 Dec 10.

forqs: forward-in-time simulation of recombination, quantitative traits and selection.

Author information

1
Bioinformatics Interdepartmental Program, University of California, Los Angeles, CA 90095 and Department of Human Genetics, University of Chicago, Chicago, IL 60637, USA.

Abstract

SUMMARY:

forqs is a forward-in-time simulation of recombination, quantitative traits and selection. It was designed to investigate haplotype patterns resulting from scenarios where substantial evolutionary change has taken place in a small number of generations due to recombination and/or selection on polygenic quantitative traits.

AVAILABILITY AND IMPLEMENTATION:

forqs is implemented as a command-line C++ program. Source code and binary executables for Linux, OSX and Windows are freely available under a permissive BSD license: https://bitbucket.org/dkessner/forqs.

PMID:
24336146
PMCID:
PMC3928523
DOI:
10.1093/bioinformatics/btt712
[Indexed for MEDLINE]
Free PMC Article

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