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Toxicol Pathol. 2014 Jan;42(1):12-44. doi: 10.1177/0192623313508020. Epub 2013 Dec 13.

Proceedings of the 2013 National Toxicology Program Satellite Symposium.

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1
1National Toxicology Program, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina, USA.

Abstract

The 2013 annual National Toxicology Program (NTP) Satellite Symposium, entitled "Pathology Potpourri," was held in Portland, Oregon, in advance of the Society of Toxicologic Pathology's 32nd annual meeting. The goal of the NTP Symposium is to present current diagnostic pathology or nomenclature issues to the toxicologic pathology community. This article presents summaries of the speakers' presentations, including diagnostic or nomenclature issues that were presented, along with select images that were used for audience voting and discussion. Some lesions and topics covered during the symposium included a caudal tail vertebra duplication in mice; nephroblastematosis in rats; ectopic C cell tumor in a hamster; granular cell aggregates/tumor in the uterus of a hamster; Pneumocystis carinii in the lung of a rat; iatrogenic chronic inflammation in the lungs of control rats; hepatoblastoma arising within an adenoma in a mouse; humoral hypercalcemia of benignancy in a transgenic mouse; acetaminophen-induced hepatotoxicity in rats; electron microscopy images of iatrogenic intraerythrocytic inclusions in transgenic mice; questionable hepatocellular degeneration/cell death/artifact in rats; atypical endometrial hyperplasia in rats; malignant mixed Müllerian tumors/carcinosarcomas in rats; differential diagnoses of proliferative lesions of the intestine of rodents; and finally obstructive nephropathy caused by melamine poisoning in a rat.

KEYWORDS:

NTP Satellite Symposium; Pneumocystis carinii; atypical endometrial hyperplasia; bronchioloalveolar hyperplasia; duplicate vertebra; gastrointestinal diverticulum; granular cell aggregates; hepatoblastoma; hepatocellular apoptosis; intraerythrocytic inclusions; malignant mixed Müllerian tumor; nephroblastematosis; obstructive nephropathy.

PMID:
24334674
PMCID:
PMC3992853
DOI:
10.1177/0192623313508020
[Indexed for MEDLINE]
Free PMC Article
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