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J Diabetes Complications. 2014 Mar-Apr;28(2):152-5. doi: 10.1016/j.jdiacomp.2013.10.007. Epub 2013 Oct 22.

Renal replacement therapy due to type 1 diabetes; time trends during 1995-2010--a Swedish population based register study.

Author information

1
Department of Clinical Sciences, Pediatrics, Umeå University, Umeå; Department of Internal Medicine, Ryhov County Hospital, Jönköping. Electronic address: cecilia.toppe@lj.se.
2
Department of Internal Medicine, Ryhov County Hospital, Jönköping.
3
Diaverum Renal Services Group, Lund, & Swedish Renal Registry, Jönköping.

Abstract

BACKGROUND:

End stage renal disease (ESRD), is the most severe complication of diabetes mellitus. This population-based study analysed time trends for start of renal replacement therapy (RRT) due to type 1 diabetes compared to type 2 diabetes and other diagnoses.

MATERIAL AND METHODS:

We used data on patients who were registered 1995-2010 in the Swedish Renal Registry, a nationwide register covering 95 % of all patients with uraemia. The patients were analysed according to their original kidney disease. The incidence was analysed by calendar year, age at start of RRT and gender.

RESULTS:

Of 17389 patients who were registered, 1833 had type 1 diabetes; 65% were men. The mean age at onset of RRT for patients with type 1 diabetes was 52.8 years which increased by more than 3 years over the studied period. The number of patients in need of RRT due to type 1 diabetes decreased, while RRT due to type 2 diabetes increased during the period studied.

CONCLUSIONS:

The overall incidence of RRT in Sweden is rather constant over the years but the need for RRT in type 1 diabetes patients decreased and patients with type 1 diabetes tend to become older at onset of RRT.

KEYWORDS:

Diabetes mellitus; Incidence; Nephropathy; Renal replacement therapy

PMID:
24332762
DOI:
10.1016/j.jdiacomp.2013.10.007
[Indexed for MEDLINE]
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