Format

Send to

Choose Destination
Trends Microbiol. 2014 Jan;22(1):42-7. doi: 10.1016/j.tim.2013.11.003. Epub 2013 Dec 9.

The emergence of mecC methicillin-resistant Staphylococcus aureus.

Author information

1
Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK. Electronic address: gkp27@cam.ac.uk.
2
Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.

Abstract

The report of methicillin-resistant Staphylococcus aureus (MRSA) encoding a divergent mecA gene in 2011 was highly significant. This homologue, designated mecC, poses diagnostic problems with the potential to be misdiagnosed as methicillin-sensitive S. aureus, with important potential consequences for individual patients and for the surveillance of MRSA. mecC MRSA have now been reported from 13 European countries and have been isolated from 14 different host species, with evidence of a recent increase in Denmark. The emergence of mecC MRSA is a topic of interest to human and veterinary microbiology, and we consider it timely to review here its discovery and subsequent investigation.

KEYWORDS:

antibiotic resistance; genome sequencing; mecC; methicillin-resistant Staphylococcus aureus (MRSA); molecular epidemiology; zoonosis

PMID:
24331435
PMCID:
PMC3989053
DOI:
10.1016/j.tim.2013.11.003
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Elsevier Science Icon for PubMed Central
Loading ...
Support Center