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Org Lett. 2014 Jan 3;16(1):212-5. doi: 10.1021/ol4032073. Epub 2013 Dec 16.

Synthesis of nitrogen-containing furanose sugar nucleotides for use as enzymatic probes.

Author information

1
Alberta Glycomics Centre and Department of Chemistry, Gunning-Lemieux Chemistry Centre, University of Alberta , Edmonton, Alberta, Canada T6G 2G2.

Abstract

The sugar nucleotides UDP-2-acetamido-2-deoxy-α-D-galactofuranose (UDP-GalfNAc) and UDP-2-azido-2-deoxy-α-D-galactofuranose (UDP-GalfN3) have been synthesized in preparative scale for the first time. These compounds are useful probes for studying the biosynthesis of glycans containing galactofuranose and/or 2-acetamido-2-deoxy-α-D-galactofuranose residues.

PMID:
24328953
DOI:
10.1021/ol4032073
[Indexed for MEDLINE]

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