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PLoS One. 2013 Dec 4;8(12):e81698. doi: 10.1371/journal.pone.0081698. eCollection 2013.

Replicability and heterogeneity of awake unrestrained canine FMRI responses.

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1
Center for Neuropolicy, Emory University, Atlanta, Georgia, United States of America.

Erratum in

  • PLoS One. 2014;9(5):e98421.

Abstract

Previously, we demonstrated the possibility of fMRI in two awake and unrestrained dogs. Here, we determined the replicability and heterogeneity of these results in an additional 11 dogs for a total of 13 subjects. Based on an anatomically placed region-of-interest, we compared the caudate response to a hand signal indicating the imminent availability of a food reward to a hand signal indicating no reward. 8 of 13 dogs had a positive differential caudate response to the signal indicating reward. The mean differential caudate response was 0.09%, which was similar to a comparable human study. These results show that canine fMRI is reliable and can be done with minimal stress to the dogs.

PMID:
24324719
PMCID:
PMC3852264
DOI:
10.1371/journal.pone.0081698
[Indexed for MEDLINE]
Free PMC Article
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