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Cancer Epidemiol. 2014 Feb;38(1):28-34. doi: 10.1016/j.canep.2013.11.002. Epub 2013 Dec 7.

Trends in stage-specific population-based survival of cancer patients in the Czech Republic in the period 2000-2008.

Author information

1
Institute of Biostatistics and Analyses, Masaryk University, Kamenice 3, 625 00 Brno, Czech Republic.
2
Department of Oncology and 1st Faculty of Medicine, Thomayer Hospital and Charles University, Vídeňská 800, 140 59 Prague, Czech Republic.
3
Department of Complex Oncology Care, Masaryk Memorial Cancer Institute, Žlutý kopec 7, 656 53 Brno, Czech Republic.
4
Department of Oncology and Radiotherapy, University Hospital Hradec Králové, Sokolská 581, 500 05 Hradec Králové, Czech Republic.
5
Department of Surgery and 2nd Faculty of Medicine, Central Military Hospital and Charles University, U Vojenské nemocnice 1200, 169 02 Prague, Czech Republic.
6
The Fingerland Department of Pathology, Charles University Medical Faculty and University Hospital Hradec Králové, Sokolská 581, 500 05 Hradec Králové, Czech Republic.
7
Gynaecological Oncologic Centre and 1st Faculty of Medicine, General University Hospital and Charles University, Apolinářská 18, 128 51 Prague, Czech Republic.
8
Department of Urology and 2nd Faculty of Medicine, University Hospital Motol and Charles University, V Úvalu 84, 150 06 Prague, Czech Republic.
9
Institute of Biostatistics and Analyses, Masaryk University, Kamenice 3, 625 00 Brno, Czech Republic. Electronic address: dusek@iba.muni.cz.

Abstract

BACKGROUND:

The objective of this study was to assess trends in overall and in stage-specific 5-year relative survival rates of the Czech cancer patients between periods 2000-2004 and 2005-2008.

METHODS:

All Czech cancer patients diagnosed between 1995 and 2008 were included in the analysis. Period analysis was employed to calculate 5-year relative survival for 21 cancers.

RESULTS:

Significant improvements in crude 5-year relative survival for 14 of 21 assessed types of cancer, including the most frequent diagnoses, such as, colorectal, prostate, breast, lung, kidney, pancreatic, and bladder cancer and melanoma, were identified. Moreover, in case of colorectal, lung, and prostate cancer, improvement in stage-specific 5-year relative survival was confirmed as statistically significant for all clinical stages. No diagnosis showed significant decrease in the 5-year relative survival. However, the 5-year relative survival remained poor in patients with metastatic cancers at diagnosis, particularly in case of liver, pancreatic, lung, and oesophageal cancer.

CONCLUSIONS:

The cancer-specific outcomes in the Czech Republic are improving. Nevertheless, despite the overall significant improvement in 5-year relative survival of most of the cancer diagnoses, the high proportion of patients primarily diagnosed with metastatic cancer still represents a substantial challenge for prevention and early detection.

KEYWORDS:

Cancer; Population-based registry; Relative survival; Stage-specific analysis

PMID:
24315848
DOI:
10.1016/j.canep.2013.11.002
[Indexed for MEDLINE]

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