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Maturitas. 2014 Jan;77(1):20-3. doi: 10.1016/j.maturitas.2013.10.012. Epub 2013 Oct 30.

Promise of uterine transplant--myth or a reality?

Author information

1
Cancer Treatment Centers of America, 600 Parkway North, Newnan, GA 30265, USA; Indiana University School of Medicine, Indianapolis, IN, USA. Electronic address: Giuseppe.DelPriore@CTCA-Hope.com.
2
Department of Radiation Oncology, Indo-American Cancer Institute and Research Center, Road# 14, Banjara Hills, Hyderabad 500034, AP, India; International Gynecologic Cancer Society Fellow, PO Box 6387, Louisville, KY 40206, USA.

Abstract

The scientific basis of uterus transplantation has been developing in parallel to other organ transplants throughout the modern period of transplant medicine. Immunosuppression and surgical techniques have been adequate for at least a decade; ethics and society have been less clearly developed. To many observers, it is still unclear if the endeavor is an overall positive or negative. Although scientific and technical challenges have been overcome, the ethical determinations will be a dynamic process while more experience continues to be gained. The most significant experience still lacking is a term gestation. Undoubtedly during a nine-month gestation, unforeseen challenges will test scientific processes and ethical assumptions. Despite dozens of animal experiments and a few animal births, no human birth has occurred to allow any definitive conclusions.

KEYWORDS:

Fertility preservation; Uterine transplant

PMID:
24314618
DOI:
10.1016/j.maturitas.2013.10.012
[Indexed for MEDLINE]

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