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Theranostics. 2013 Sep 19;3(10):731-40. doi: 10.7150/thno.5162.

Proton therapy verification with PET imaging.

Author information

1
Center for Advanced Medical Imaging Sciences, NMMI Division, Radiology Department, Massachusetts General Hospital, Harvard Medical School, Boston.

Abstract

Proton therapy is very sensitive to uncertainties introduced during treatment planning and dose delivery. PET imaging of proton induced positron emitter distributions is the only practical approach for in vivo, in situ verification of proton therapy. This article reviews the current status of proton therapy verification with PET imaging. The different data detecting systems (in-beam, in-room and off-line PET), calculation methods for the prediction of proton induced PET activity distributions, and approaches for data evaluation are discussed.

KEYWORDS:

PET imaging.; proton range verification; proton therapy

PMID:
24312147
PMCID:
PMC3840408
DOI:
10.7150/thno.5162
[Indexed for MEDLINE]
Free PMC Article

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