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Comput Biol Med. 2013 Dec;43(12):2028-35. doi: 10.1016/j.compbiomed.2013.09.011. Epub 2013 Sep 25.

Accelerating in silico research with workflows: a lesson in Simplicity.

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nSilico LifeSciences, Ltd., Melbourne Building, Bishopstown, Cork, Ireland.


Bioinformatics is the application of computer science and related disciplines to the field of molecular biology. While there are currently several web based and desktop tools available for biologists to perform routine bioinformatics tasks, these tools often require users to manually and repeatedly co-ordinate multiple applications before reaching a result. In an effort to reduce time and error, workflow tools have been developed to automate these tasks. However, many of these tools require expert knowledge of the techniques and supporting databases which more often than not lies outside the scope of most biologists. Herein, we describe the development of sequence information management platform (Simplicity), a workflow-based bioinformatics management tool, which allows non-bioinformaticians to rapidly annotate large amounts of DNA and protein sequence data.


Bioinformatics; Computational biology workflow; Genomics; Simplicity; Usability; annotation

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