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J Am Acad Child Adolesc Psychiatry. 2013 Dec;52(12):1294-1303.e1. doi: 10.1016/j.jaac.2013.09.008. Epub 2013 Sep 27.

Preschool anxiety disorders in pediatric primary care: prevalence and comorbidity.

Author information

1
Center for Developmental Epidemiology, Duke University Medical Center. Electronic address: lauren.franz@dm.duke.edu.

Abstract

OBJECTIVE:

We sought to establish prevalence rates and detail patterns of comorbidity for generalized anxiety disorder, separation anxiety disorder, and social phobia in preschool-aged children.

METHOD:

The Duke Preschool Anxiety Study, a screen-stratified, cross-sectional study, drew from pediatric primary care and oversampled for children at risk for anxiety. A total of 917 parents of preschool children (aged 2-5 years) completed the Preschool Age Psychiatric Assessment.

RESULTS:

Generalized anxiety disorder, separation anxiety disorder, and social phobia are common in preschool-aged children attending pediatric primary care. Three-fourths of preschoolers with an anxiety disorder only had a single anxiety disorder. Generalized anxiety disorder displayed the greatest degree of comorbidity: with separation anxiety disorder (odds ratio [OR] = 4.1, 95% CI = 2.0-8.5), social phobia (OR = 6.4, 95% CI = 3.1-13.4), disruptive behavior disorders (OR = 5.1, 95% CI = 1.6-15.8), and depression (OR = 3.7, 95% CI = 1.1-12.4).

CONCLUSIONS:

The weakness of association between generalized anxiety disorder and depression stands in contrast to substantial associations between these 2 disorders reported in older individuals. Attenuated associations in preschool-aged children could translate into clinical opportunities for targeted early interventions, aimed at modifying the developmental trajectory of anxiety disorders.

KEYWORDS:

comorbidity; pediatric primary care; preschool anxiety disorders; prevalence

PMID:
24290462
PMCID:
PMC3896976
DOI:
10.1016/j.jaac.2013.09.008
[Indexed for MEDLINE]
Free PMC Article

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