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Am J Kidney Dis. 2014 Apr;63(4):652-5. doi: 10.1053/j.ajkd.2013.09.020. Epub 2013 Nov 27.

Skin involvement in atypical hemolytic uremic syndrome.

Author information

1
Center for HUS Prevention, Control and Management, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: ardissino@centroseu.org.
2
Center for HUS Prevention, Control and Management, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.
3
Dermatology Unit, Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico, Milan, Italy.

Abstract

Skin involvement in atypical hemolytic uremic syndrome (aHUS) is very uncommon and therefore often unrecognized as a specific symptom of aHUS. We describe 3 cases of patients with aHUS who developed skin lesions that completely recovered when disease-specific treatment was established. These cases suggest that in individuals with aHUS, when skin lesions of unknown origin occur, the possibility that they are due to thrombotic microangiopathy should be considered.

KEYWORDS:

Haemolytic uremic syndrome; case report; eculizumab; plasma exchange; skin; thrombotic microangiopathy

PMID:
24290245
DOI:
10.1053/j.ajkd.2013.09.020
[Indexed for MEDLINE]
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