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Med Eng Phys. 2014 Apr;36(4):530-3. doi: 10.1016/j.medengphy.2013.11.004. Epub 2013 Nov 28.

Quantification of photocatalytic oxygenation of human blood.

Author information

1
Department of Physics, Indian Institute of Technology - Madras, Chennai, India.
2
Department of Physics, Indian Institute of Technology - Madras, Chennai, India; Department of Cardiothoracic Surgery, Apollo Hospital, Chennai, India. Electronic address: paulramesh@gmail.com.
3
Department of Perfusion, Apollo Hospital, Chennai, India.
4
Department of Endocrinology, Apollo Hospital, Chennai, India.

Abstract

Photocatalytic oxygenation of human blood is an emerging concept based on the principle of photocatalytic splitting of water into oxygen and hydrogen. This communication reports: (i) a design of a photocatalytic cell (PC) that separates the blood from UV (incident) radiation source, (ii) a pH, temperature and flow controlled circuit designed for quantifying the oxygenation of human blood by photocatalysis and (iii) measuring the current efficacy of ITO/TiO2 nano thin films in oxygenating human blood in a dynamic circuit in real time. The average increase in oxygen saturation was around 5% above baseline compared to control (p<0.0005). We believe this is one of the first attempts to quantify photocatalytic oxygenation of human blood under controlled conditions.

KEYWORDS:

Oxygenation of human blood; Photocatalysis; Prototype PC cell; Prototype circuit; Quantification

PMID:
24290134
DOI:
10.1016/j.medengphy.2013.11.004
[Indexed for MEDLINE]

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