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Endocrinol Metab Clin North Am. 2013 Dec;42(4):833-47. doi: 10.1016/j.ecl.2013.08.002.

Complications of the diabetic foot.

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Department of Plastic Surgery, Georgetown School of Medicine, Center for Wound Healing & Hyperbaric Medicine, MedStar Georgetown University Hospital, 3800 Reservoir Road Northwest, Washington, DC 20007, USA.


The diabetic foot is at high risk for complications because of its role in ambulation. Peripheral neuropathy and peripheral vascular disease can lead to chronic foot ulcers, which are at high risk for infection, in part attributable to areas of high pressure caused by lack of tolerance of the soft tissue and bone and joint deformity. If left untreated, infection and ischemia lead to tissue death, culminating in amputation. Treatment strategies include antibiosis, topical therapies, offloading, debridement, and surgery. A multidisciplinary team approach is necessary in the prevention and treatment of complications of the diabetic foot.


Amputation; Diabetes; Infection; Multidisciplinary; Ulcer; Wound

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