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ANZ J Surg. 2015 Sep;85(9):668-72. doi: 10.1111/ans.12476. Epub 2013 Nov 28.

Randomized controlled trial of laparoscopic anterior 180° partial versus posterior 270° partial fundoplication.

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Department of Surgery, Flinders University, Adelaide, South Australia, Australia.
Discipline of Surgery, University of Adelaide, Adelaide, South Australia, Australia.
Department of Surgery, University of Queensland, Brisbane, Queensland, Australia.



Previous trials show good outcomes following anterior and posterior partial versus Nissen fundoplication for gastro-oesophageal reflux. However, it is unclear which partial fundoplication performs best. This study compared anterior 180° versus posterior 270° fundoplication.


At three hospitals, patients were randomized to anterior 180° versus posterior 270° partial fundoplication, and clinical outcomes were determined using a structured questionnaire at 3, 6 and 12 months. Heartburn, dysphagia and satisfaction were assessed using 0-10 analoue scales, and adverse outcomes and side effects were determined. Endoscopy, manometry and pH monitoring were performed 6 months after surgery.


Forty-seven patients were randomized to anterior (n = 23) versus posterior (n = 24) fundoplication. Clinical outcomes for 93-98% of patients were available at each follow-up point. At 12 months, the mean heartburn score was higher following anterior fundoplication (2.7 versus 0.8, P = 0.045), although differences were not significant at earlier follow-up. Conversely, following posterior fundoplication, patients were less able to belch at 3 (56% versus 16%, P = 0.013) and 6 months (43% versus 9%, P = 0.017). No significant differences were demonstrated for dysphagia. Both groups had high rates of satisfaction with the outcome - 85% versus 86% satisfied at 12 months follow-up.


Both partial fundoplications are effective treatments for gastro-oesophageal reflux. Posterior partial fundoplication is associated with less reflux symptoms offset by more side effects.


fundoplication; gastro-oesophageal reflux disease; laparoscopy; randomized controlled trial

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