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Reprod Biomed Online. 2014 Jan;28(1):116-24. doi: 10.1016/j.rbmo.2013.09.020. Epub 2013 Sep 27.

What is the societal burden of endometriosis-associated symptoms? a prospective Belgian study.

Author information

1
Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Belgium.
2
Leuven University Fertility Center, University Hospitals Leuven, Belgium.
3
Department of Clinical Epidemiology and Medical Technology Assessment, Maastricht University Medical Centre, Maastricht, The Netherlands.
4
Department of Obstetrics and Gynaecology, Research Institute GROW, Maastricht University Medical Centre, Maastricht, The Netherlands.
5
Department of Pharmaceutical and Pharmacological Sciences, KU Leuven, Belgium. Electronic address: steven.simoens@pharm.kuleuven.be.

Abstract

Endometriosis is a complex disease that affects a large number of women of reproductive age and imposes a significant burden on patients and society. The aim of this study was to evaluate diagnosis, comorbidities, healthcare resource use, treatment patterns, costs and quality of life of women with endometriosis seen in a Belgian tertiary care centre. A total of 134 patients were included in a prospective questionnaire-based cost-of-illness study. Patients were diagnosed after a median delay of 2 years after onset of symptoms. Almost all patients reported having at least one comorbidity. Total annual costs per patient were €9872 (95% confidence interval €7930–11,870), with costs of productivity loss representing 75% of total costs. Hospitalizations, surgeries, infertility treatments, pain and anxiety increased total costs significantly (P 0.001). Patients generated an average of 0.82 QaLY over a 1-year time horizon. This study showed that direct and indirect costs attributable to endometriosis-associated symptoms are substantial. Earlier diagnosis and cost-effective treatment of endometriosis may decrease productivity loss, quality of life impairment and healthcare consumption and consequently reduce total costs to patients and society.

KEYWORDS:

comorbidities; costs; endometriosis; quality of life; resource use; treatment

PMID:
24268732
DOI:
10.1016/j.rbmo.2013.09.020
[Indexed for MEDLINE]

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