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Eur J Vasc Endovasc Surg. 2014 Feb;47(2):187-95. doi: 10.1016/j.ejvs.2013.10.017. Epub 2013 Oct 30.

Catheter-directed foam sclerotherapy of great saphenous veins in combination with pre-treatment reduction of the diameter employing the principals of perivenous tumescent local anesthesia.

Author information

1
Department of Dermatology, University of Schleswig-Holstein, Campus Luebeck, Germany.
2
Dermatological Practise, Hamburg, Germany.
3
Department of Dermatology, University of Schleswig-Holstein, Campus Luebeck, Germany. Electronic address: birgit.kahle@uksh.de.

Abstract

OBJECTIVES:

The aim of this study was to evaluate occlusion rates of great saphenous veins (GSV) with a diameter between 5-10 mm that received a pre-treatment size reduction via perivenous tumescent application (TA) followed by catheter-directed foam sclerotherapy (CDFS).

METHODS:

A prospective blinded randomized clinical trial comparing the occlusion rates of GSV at 1-, 6-, and 12-month follow-up. Fifty patients were included and randomized into two groups. CDFS was performed accessing the GSV at knee level and applying 8 mL of 2% polidocanol-foam (EasyFoam) while the catheter was withdrawn. Strictly perivenous TA was performed in group 1 before applying the sclerosant agent. Occlusion rates and clinical scores were assessed by blinded examiners.

RESULTS:

After 12 months in group 1 full occlusion was achieved in 73.9%, partial occlusion in 8.7%, and 17.4% were classified as treatment failure. In group 2, 75% of the targeted GSV were fully occluded, 20% were partially occluded, and 5% were diagnosed as treatment failure. Both groups showed a significant reduction of the vein diameter. Patient's tolerance and satisfaction with the treatment was high in both groups.

CONCLUSION:

No benefit could be found using additional TA to reduce the vein diameter before the treatment.

KEYWORDS:

Catheter-directed sclerotherapy; Foam sclerotherapy; Tumescence; Varicose veins; Venous insufficiency

PMID:
24268395
DOI:
10.1016/j.ejvs.2013.10.017
[Indexed for MEDLINE]
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