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Health Rep. 2013 Nov;24(11):3-13.

Seroprevalence of hepatitis B and C virus infections: Results from the 2007 to 2009 and 2009 to 2011 Canadian Health Measures Survey.

Author information

1
Health Analysis Division, Statistics Canada, Ottawa, Ontario, K1A 0T6. michelle.rotermann@statcan.gc.ca

Abstract

BACKGROUND:

Chronic hepatitis B (HBV) and C (HCV) virus infections can lead to liver failure, liver cancer, and death. In Canada, prevalence studies of HBV and HCV have been limited to regional and special populations.

DATA AND METHODS:

Data are from cycles 1 (2007 to 2009) and 2 (2009 to 2011) of the Canadian Health Measures. Socio-demographic, health and lifestyle information was obtained via a household questionnaire; blood samples collected at mobile examination centres were used to identify present and resolved HBV infections, vaccine-induced HBV immunity, and HCV infections.

RESULTS:

The seroprevalence of present HBV infection among the population aged 14 to 79 was 0.4%, representing an estimated 111,800 individuals. Another 4.2% had evidence of a previous HBV infection. Nearly 30% had vaccine-induced HBV immunity. The seroprevalence of HCV infection was 0.5%, representing an estimated 138,600. More than half of people with laboratory-confirmed HBV and 70% with laboratory-confirmed HCV were unaware of their infections.

INTERPRETATION:

This is the first Canadian study to report laboratory-confirmed seroprevalence of HBV and HCV infections based on a nationally representative household sample. Substantial percentages of younger Canadians have vaccine-induced HBV immunity.

KEYWORDS:

biological specimens, data pooling, direct measures, disease notification, sexually transmitted diseases and blood-borne infectionsaging; blood-borne infections; data pooling; direct measures; disease notification; sexually transmitted diseases

PMID:
24259199
[Indexed for MEDLINE]
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