Format

Send to

Choose Destination
Mod Rheumatol. 2015 Jul;25(4):642-5. doi: 10.3109/14397595.2013.844306. Epub 2013 Nov 4.

TNF-alpha inhibitors in Systemic Lupus Erythematosus. A case report and a systematic literature review.

Author information

1
Department of Clinical and Experimental Medicine, Rheumatology Unit, University of Pisa , Pisa Italy.

Abstract

Joint involvement is a common manifestation of systemic lupus erythematosus (SLE) and is described as a non-erosive mild synovitis. However some SLE patients may present a more severe joint involvement requiring aggressive therapy. We describe the case of a SLE patient with a severe arthritis unresponsive to methotrexate, successfully treated with anti-TNF-alpha drug as induction therapy and we report the results of a systematic literature review on the use of TNF-alpha inhibitors in SLE.

KEYWORDS:

Anti-TNF therapy; Joint involvement; Systemic lupus erythematosus; treatment targets

PMID:
24252029
DOI:
10.3109/14397595.2013.844306
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Taylor & Francis
Loading ...
Support Center