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Mar Drugs. 2013 Nov 14;11(11):4585-93. doi: 10.3390/md11114585.

Discovery of new eunicellin-based diterpenoids from a Formosan soft coral Cladiella sp.

Author information

1
Graduate Institute of Marine Biotechnology, National Dong Hwa University, Pingtung 944, Taiwan. pjsung@nmmba.gov.tw.

Abstract

A new eunicellin diterpenoid, cladieunicellin I (1), and a new natural eunicellin, litophynin I diacetate (2), were isolated from a Formosan soft coral identified as Cladiella sp. The structures of eunicellins 1 and 2 were elucidated by spectroscopic methods and by comparison of the spectral data with those of related analogues. Eunicellin 1 exhibited significant cytotoxicity toward the DLD-1 human colorectal adenocarcinoma cells.

PMID:
24240980
PMCID:
PMC3853747
DOI:
10.3390/md11114585
[Indexed for MEDLINE]
Free PMC Article
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