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J Clin Neurosci. 2014 May;21(5):874-6. doi: 10.1016/j.jocn.2013.06.025. Epub 2013 Sep 11.

Intracranial pseudolymphoma presenting with grand mal seizures.

Author information

1
Wake Forest School of Medicine, Department of Neurology, 1 Medical Center Boulevard, Box 2669, Winston Salem, NC 27157, USA. Electronic address: rstrowd1@jhmi.edu.
2
Wake Forest School of Medicine, Department of Neurosurgery, Winston Salem, NC, USA.
3
Wake Forest School of Medicine, Department of Pathology, Winston Salem, NC, USA.

Abstract

Primary central nervous system lymphoproliferative disorders comprise a heterogenous group of intracranial disease, predominantly of the high-grade non-Hodgkin's lymphoma type. We report a 56-year-old woman who developed new-onset grand mal seizures and was found to have two small uniformly enhancing dural-based lesions, which were radiologically concerning for meningiomas. Biopsy demonstrated findings consistent with benign, reactive lymphoid tissue. The patient's seizures resolved post-operatively. To our knowledge, this is the first reported patient with intracranial pseudolymphoma presenting as grand mal seizures. This case highlights this rare differential consideration in a patient with symptomatic dural-based lesion.

KEYWORDS:

Intracranial pseudolymphoma; Meningioma; Neuroradiology; Seizure

PMID:
24239229
DOI:
10.1016/j.jocn.2013.06.025
[Indexed for MEDLINE]

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