Format

Send to

Choose Destination
Arch Bronconeumol. 2013 Dec;49(12):523-8. doi: 10.1016/j.arbres.2013.09.006. Epub 2013 Nov 12.

Lung transplantation in children. Specific aspects.

Author information

1
Unidad de Neumología Pediátrica y Fibrosis Quística, Hospital Universitari Vall d'Hebron, Barcelona, España; Departament de Pediatria, d'Obstetricia i Ginecologia i de Medicina Preventiva, Universitat Autònoma de Barcelona, Barcelona, España. Electronic address: aroman@vhebron.net.

Abstract

Lung transplantation has become in recent years a therapeutic option for infantswith terminal lung disease with similar results to transplantation in adults.In Spain, since 1996 114 children lung transplants have been performed; this corresponds to3.9% of the total transplant number.The most common indication in children is cystic fibrosis, which represents between 70-80% of the transplants performed in adolescents. In infants common indications areinterstitial lung disease and pulmonary hypertension.In most children a sequential double lung transplant is performed, generally with the help ofextracorporeal circulation. Lung transplantation in children presents special challenges in monitoring and follow-up, especially in infants, given the difficulty in assessing lung function and performing transbronchial biopsies.There are some more specific complications in children like postransplant lymphoproliferative syndrome or a greater severity of respiratory virus infections .After lung transplantation children usually experiment a very important improvement in their quality of life. Eighty eight per cent of children have no limitations in their activity after 3 years of transplantation.According to the registry of the International Society for Heart & Lung Transplantation (ISHLT) survival at 5 years of transplantation is 54% and at 10 years is around 35%.

KEYWORDS:

Children; Cystic fibrosis; Fibrosis quística; Hipertensión pulmonar; Interstitial pneumonia; Lung transplant; Neumopatías intersticiales; Niños; Pulmonary hypertension; Trasplante pulmonar

PMID:
24239132
DOI:
10.1016/j.arbres.2013.09.006
[Indexed for MEDLINE]
Free full text

Supplemental Content

Full text links

Icon for Ediciones Doyma, S.L.
Loading ...
Support Center