Format

Send to

Choose Destination
Pediatr Clin North Am. 2013 Dec;60(6):1383-91. doi: 10.1016/j.pcl.2013.08.008. Epub 2013 Oct 4.

Thalassemias.

Author information

1
Division of Hematology/Oncology, Ann and Robert H. Lurie Children's Hospital of Chicago, 225 East Chicago Avenue, Box #30, Chicago, IL 60611, USA.

Abstract

The thalassemia syndromes are hemoglobin disorders that result from significantly reduced or absent synthesis of either the α- or β-globin chains. The result is a chronic hemolytic anemia with ineffective erythropoiesis and bone marrow overstimulation. This article reviews current diagnostic approaches, complications, and disease management of thalassemia.

KEYWORDS:

Anemia; Hemoglobinopathies; Iron overload; Thalassemia

PMID:
24237977
DOI:
10.1016/j.pcl.2013.08.008
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center