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Hum Exp Toxicol. 2014 Aug;33(8):878-81. doi: 10.1177/0960327113510536. Epub 2013 Nov 12.

Rhabdomyolysis induced by excessive coffee drinking.

Author information

1
Department of Medicine, Armed Forces Taoyuan General Hospital, Taoyuan, Taiwan Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
2
Department of Pediatrics, Armed Forces Taoyuan General Hospital, Taoyuan, Taiwan.
3
Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.
4
Division of Nephrology, Department of Medicine, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan l521116@gmail.com.

Abstract

Excessive ingestion of caffeine-containing beverages is a rare cause of rhabdomyolysis. Here, we describe the case of a 44-year-old woman presented with nausea, vomiting, palpitations, and tea-colored urine 6 h after drinking a liter of black coffee containing approximately 565 mg of caffeine for mental alertness. Laboratory studies were notable for myoglobinuria and markedly elevated plasma creatine kinase (CK) level of 7315 U/L. With volume expansion and alkalization, her plasma CK level returned to normal within 5 days. Rhabdomyolysis should be considered a potential health hazard from excessive consumption of caffeine-containing products.

KEYWORDS:

Caffeine; coffee; rhabdomyolysis

PMID:
24220878
DOI:
10.1177/0960327113510536
[Indexed for MEDLINE]

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