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J Am Anim Hosp Assoc. 2014 Jan-Feb;50(1):59-61. doi: 10.5326/JAAHA-MS-5951. Epub 2013 Nov 11.

Use of IV lipid emulsion for treatment of ivermectin toxicosis in a cat.

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Department of Small Animal Clinical Sciences, College of Veterinary Medicine, University of Florida, Gainesville, FL.


Ivermectin toxicosis in cats is infrequently reported. IV lipid emulsion (ILE) is a novel treatment in veterinary medicine that has been used for amelioration of adverse effects seen with multiple lipid soluble compounds. Previously, ILE has been investigated in experimental models with rats, rabbits, pigs, and dogs, mainly for resuscitation of cardiopulmonary arrest and treatment of hypotension due to local anesthetic drug overdose. There are few case reports in veterinary medicine of using ILE for drug toxicity. Only one feline case has been reported, with IV lipids used for treatment of lidocaine toxicity. This report describes a case of ivermectin toxicosis in a 1 yr old domestic shorthair that was safely and successfully treated using ILE.

[Indexed for MEDLINE]

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