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Forensic Sci Int. 2014 Jan;234:e14-20. doi: 10.1016/j.forsciint.2013.10.015. Epub 2013 Oct 18.

Postmortem detection of 25I-NBOMe [2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine] in fluids and tissues determined by high performance liquid chromatography with tandem mass spectrometry from a traumatic death.

Author information

1
Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: jlpoklis@vcu.edu.
2
Hillsborough County Medical Examiner Department, Tampa, FL, USA.
3
Tampa Police Department, Tampa, FL, USA.
4
Department of Pharmacology and Toxicology, Virginia Commonwealth University, Richmond, VA, USA; Department of Pathology, Virginia Commonwealth University, Richmond, VA, USA; Department of Forensic Science, Virginia Commonwealth University, Richmond, VA, USA. Electronic address: apoklis@mcvh-vcu.edu.

Abstract

We present a traumatic fatality of a 19-year-old man who had ingested blotter paper containing 25I-NBOMe [2-(4-iodo-2,5-dimethoxyphenyl)-N-[(2-methoxyphenyl)methyl]ethanamine]. Postmortem specimens were analyzed by high performance liquid chromatography with tandem mass spectrometry (HPLC/MS/MS). Toxicology findings for fluids based upon blood or urine calibrators were as follows: peripheral blood, 405 pg/mL; heart blood, 410 pg/mL; urine, 2.86 ng/mL; and vitreous humor, 99 pg/mL. While findings based upon the method of standard additions were: gastric contents, 7.1 μg total; bile, 10.9 ng/g; brain, 2.54 ng/g and liver, 7.2 ng/g. To our knowledge the presented case is the first postmortem case of 25I-NBOMe intoxication documented by toxicological analysis of tissues and body fluids.

KEYWORDS:

25I-NBOMe; Bath salts; Designer drugs; HPLC/MS/MS

PMID:
24215811
PMCID:
PMC3969735
DOI:
10.1016/j.forsciint.2013.10.015
[Indexed for MEDLINE]
Free PMC Article
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