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Curr Biol. 2013 Nov 4;23(21):R956-9. doi: 10.1016/j.cub.2013.09.032.

Cilium assembly: delivery of tubulin by kinesin-2-powered trains.

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1
Department of Molecular Biology and Genetics, Bogazici University, Istanbul, Turkey; Department of Molecular and Cell Biology, University of California at Davis, Davis, CA 95616, USA. Electronic address: jmscholey@ucdavis.edu.

Abstract

The kinesin-2-driven anterograde transport of intraflagellar transport (IFT) trains has long been suspected to deliver cargo consisting of tubulin subunits for assembly at the axoneme tip. Important new work identifies the tubulin binding site on IFT trains that is responsible for this cargo transport.

PMID:
24200322
DOI:
10.1016/j.cub.2013.09.032
[Indexed for MEDLINE]
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