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Nat Cell Biol. 2013 Nov;15(11):1261-3. doi: 10.1038/ncb2876.

Slipping past the spindle assembly checkpoint.

Author information

1
Laboratory of Chemistry and Cell Biology, The Rockefeller University, 1230 York Avenue, New York, New York 10065, USA.

Abstract

Error-free genome segregation depends on the spindle assembly checkpoint (SAC), a signalling network that delays anaphase onset until chromosomes have established proper spindle attachments. Three reports now quantitatively examine the sensitivity and robustness of the SAC response.

PMID:
24189515
DOI:
10.1038/ncb2876
[Indexed for MEDLINE]

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