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J Nutr Educ Behav. 2014 Mar-Apr;46(2):90-101. doi: 10.1016/j.jneb.2013.09.005. Epub 2013 Oct 30.

Dietary interventions and quality of life: a systematic review of the literature.

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Division of Preventive Medicine, Department of Medicine, School of Medicine, University of Alabama at Birmingham, Birmingham, AL; Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL; Comprehensive Cancer Center, University of Alabama at Birmingham, Birmingham, AL. Electronic address:
Department of Biostatistics, Section on Statistical Genetics, University of Alabama at Birmingham; Birmingham, AL.
Department of Epidemiology and Prevention, Wake Forest School of Medicine, Wake Forest Baptist Medical Center, Winston Salem, NC.
Nutrition Obesity Research Center, University of Alabama at Birmingham, Birmingham, AL; Department of Epidemiology, School of Public Health; University of Alabama at Birmingham, Birmingham, AL.



To systematically review the literature to examine whether there has been adequate assessment of the effects of dietary intervention on quality of life (QOL) independent of weight loss, assess which instruments are being used to measure nutrition-related QOL, identify gaps in the literature, and suggest future directions.


Systematic review guided by the Preferred Reporting Items for Systematic Reviews and Meta-Analyses Statement.


A total of 24 studies were eligible for inclusion. The Short Form-36 Health Survey was the most widely used instrument to assess QOL. Other disease-specific instruments were used. Several different dietary approaches (eg, low carbohydrate, low calorie, low fat, combinations) were recommended. Across studies, QOL generally improved after participating in behavioral weight loss interventions, but findings revealed a lack of evidence to definitively determine whether reported changes in QOL were a result of weight loss or independent of it.


It is important to consider how making broad dietary recommendations for all individuals might affect overall QOL in both positive and negative directions when considering factors other than weight loss and health improvement. If dietary interventions are adversely affecting QOL in other domains (eg, social, economic) and this relationship is not being detected or reported by current research practices, barriers for successful and sustainable dietary changes may not be fully understood.


diet; quality of life; review; weight loss

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