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Clin Infect Dis. 2014 Feb;58(3):396-9. doi: 10.1093/cid/cit715. Epub 2013 Oct 30.

Escherichia coli dysbiosis correlates with gastrointestinal dysfunction in children with cystic fibrosis.

Author information

1
Departments of Pediatrics.

Abstract

Cystic fibrosis gastrointestinal disease includes nutrient malabsorption and intestinal inflammation. We show that the abundances of Escherichia coli in fecal microbiota were significantly higher in young children with cystic fibrosis than in controls and correlated with fecal measures of nutrient malabsorption and inflammation, suggesting that E. coli could contribute to cystic fibrosis gastrointestinal dysfunction.

KEYWORDS:

Escherichia coli; cystic fibrosis; inflammation; malabsorption; microbiota

PMID:
24178246
PMCID:
PMC3890337
DOI:
10.1093/cid/cit715
[Indexed for MEDLINE]
Free PMC Article

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