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Acta Paediatr. 2014 Mar;103(3):249-55. doi: 10.1111/apa.12487. Epub 2013 Dec 20.

Meta-analysis shows limited evidence for using Lactobacillus acidophilus LB to treat acute gastroenteritis in children.

Author information

1
Department of Paediatrics, The Medical University of Warsaw, Warsaw, Poland.

Abstract

A meta-analysis of four randomised controlled trials of varying methodological quality, involving 304 children aged 1-48 months, showed that Lactobacillus acidophilus LB (LB) reduced the duration of diarrhoea in hospitalised, but not outpatient, children compared with a placebo. The chance of a cure on day three was similar in both groups, but LB increased the chance of cure on day four.

CONCLUSION:

There is limited evidence to recommend LB for treating paediatric diarrhoea.

KEYWORDS:

Diarrhoea; Microbiota; Probiotics; RCT; Systematic review

PMID:
24175943
DOI:
10.1111/apa.12487
[Indexed for MEDLINE]

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