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J Indian Soc Periodontol. 2013 Sep;17(5):644-7. doi: 10.4103/0972-124X.119284.

Sinus lift tissue engineering using autologous pulp micro-grafts: A case report of bone density evaluation.

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Dental Clinic, Don Orione Hospital, Bergamo, Italy.



Although autografts are the standard procedure for bone grafting, the use of bone regeneration by means of dental pulp stem cell is an alternative that opens a new era in this field. Rigenera Protocol is a new technique able to provide the surgeon autologous pulp micro-grafts.


At the Department of Oral Surgery, Don Orione Hospital, Bergamo, Italy, one patient underwent sinus lift elevation with pulp stem micro-grafts gentle poured onto collagen sponge. A CT scan control was performed after 4 months and DICOM data were processed with medical imaging software which gives the possibility to use a virtual probe to extract the bone density. Pearson's Chi-square test was used to investigate difference in bone density (BD) between native and newly formed bone.


BD in newly formed bone is about the double of native bone.


This report demonstrated that micro-grafts derived from dental pulp poured onto collagen sponge are a useful method for bone regeneration in atrophic maxilla.


Bone; homograft; jaw; reconstruction; resorption; stem cell

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