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Semin Ophthalmol. 2015;30(5-6):417-9. doi: 10.3109/08820538.2013.833258. Epub 2013 Oct 30.

Clinical Course of a Presumed Metastatic Uveal Melanoma to the Contralateral Choroid.

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a Department of Ophthalmology , University Hospital of Bellvitge, Barcelona University , Barcelona , Spain and.
b Department of Ophthalmology , Hospital Clinic of Barcelona, Barcelona University , Barcelona , Spain.


We present the ultrasound and optic coherence tomography follow-up of a presumed choroidal metastasis from a contralateral melanoma. A 53-year-old male was diagnosed with uveal melanoma with extraescleral extension in his left eye. A year later, the fundus examination revealed a flat, gray-green, pigmented choroidal lesion in the right eye. The ultrasonography showed a mass, almost flat, and all these findings were compatible with a choroidal melanocytic lesion with risk factors for growth. One month later, melanocytic skin lesions appeared on the scalp, as well as small tumors. Three months later, an ultrasonography on B scan showed a growth of the tumor size. The patient developed a progressive deterioration and died. Three possibilities can explain the occurrence of a choroidal pigmented tumor in the contralateral eye: first, bilateral primary choroidal melanomas; second, both choroidal tumors are metastatic in origin from an unknown primary melanoma; and third, the contralateral tumor is a metastatic tumor from the primary choroidal melanoma.


Choroidal metastasis; melanoma; metastatic melanoma; ocular oncology; uveal melanoma

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