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J Clin Pathol. 2014 Mar;67(3):272-5. doi: 10.1136/jclinpath-2013-201854. Epub 2013 Oct 29.

The value of archival tissue blocks in understanding breast cancer biology.

Author information

1
Leeds Institute of Cancer and Pathology, University of Leeds, , Leeds, UK.

Abstract

Pathological reporting of breast cancer has evolved alongside scientific advances. Such advances have led to recognition of different molecular classes of breast cancer resulting in improved disease management. The aim of this study was to establish whether these advances could be applied to archival breast cancer cases dating from the 1940s to assess historical trends. Important observations included the marked differences in pathological reporting, size of tumour and in ERĪ± expression throughout the decades.

KEYWORDS:

BREAST CANCER; BREAST PATHOLOGY; TAXONOMY

PMID:
24170212
DOI:
10.1136/jclinpath-2013-201854
[Indexed for MEDLINE]

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