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Arch Gynecol Obstet. 2014 Mar;289(3):479-89. doi: 10.1007/s00404-013-3064-9. Epub 2013 Oct 30.

The role of lactobacilli and probiotics in maintaining vaginal health.

Author information

1
CBQF, Centro de Biotecnologia e Química Fina, Escola Superior de Biotecnologia, Centro Regional do Porto da Universidade Católica Portuguesa, Rua Dr. António Bernardino Almeida, 4200-072, Porto, Portugal.

Abstract

BACKGROUND:

The vaginal microbiota of healthy women consists typically of a diversity of anaerobic and aerobic microorganisms. Lactobacilli are the most prevalent and often numerically dominant microorganisms and are relevant as a barrier to infection. The capacity of lactobacilli to adhere and compete for adhesion sites in the vaginal epithelium and the capacity to produce antimicrobial compounds (hydrogen peroxide, lactic acid, bacteriocin-like substances), are important in the impairment of colonization by pathogens.

OBJECTIVE:

This review summarizes the role of lactic acid bacteria in preventing illness of the host, including bacterial vaginosis, yeast vaginitis, urinary tract infection and sexually transmitted diseases.

CONCLUSIONS:

The administration of probiotics that colonize the vaginal tract can be important in maintaining a normal urogenital health and also to prevent or treat infections.

PMID:
24170161
DOI:
10.1007/s00404-013-3064-9
[Indexed for MEDLINE]

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