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Cell Res. 2014 Jan;24(1):5-6. doi: 10.1038/cr.2013.142. Epub 2013 Oct 29.

An antibiotic-altered microbiota provides fuel for the enteric foe.

Author information

1
Department of Microbiology & Immunology, University of British Columbia, Vancouver, BC, V6T 1Z4.
2
Department of Pediatrics, Child & Family Research Institute, Vancouver, BC, V5Z 4H4.

Abstract

Antibiotic therapies disrupt the intestinal microbiota and render the host susceptible to enteric infections. A recent report by Ng et al. explores the ability of two intestinal pathogens (Salmonella enterica serovar Typhimurium and Clostridium difficile) to use this disruption to their advantage and consume host carbohydrates that would otherwise be unavailable in the presence of a normal gut microbiota.

PMID:
24165893
PMCID:
PMC3879700
DOI:
10.1038/cr.2013.142
[Indexed for MEDLINE]
Free PMC Article

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