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Natl J Maxillofac Surg. 2013 Jan;4(1):90-3. doi: 10.4103/0975-5950.117874.

Non-syndromic odontogenic keratocysts: A rare case report.

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Department of Oral Surgery, Jodhpur Dental College General Hospital, Jodhpur, Rajasthan, India.


Odontogenic keratocysts are very well documented in the literature. Multiple odontogenic keratocysts (OKCs) are one of the most frequent features of nevoid basal cell carcinoma syndrome (NBCCS). It is linked with mutation in the PTCH gene (human homolog of the drosophila segment polarity gene, "patched",). Partial expression of the gene may result in occurrence of only multiple recurring OKC without any associated systemic findings. A rare case of multiple odontogenic keratocysts unassociated with any syndrome is reported, so as to add to the growing number of such cases in the literature. The possibility of this case being a partial expression of the Gorlin-Goltz syndrome is discussed.


Gorlin-Goltz syndrome; Protein patched homolog gene; jaw cysts; nevoid basal cell carcinoma syndrome; odontogenic keratocysts

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