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J Cutan Aesthet Surg. 2013 Jul;6(3):148-51. doi: 10.4103/0974-2077.118410.

A study on fractional erbium glass laser therapy versus chemical peeling for the treatment of melasma in female patients.

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Punjab Health Systems Corporation, Ferozepur, Punjab, India.



Melasma is a commonly acquired hypermelanosis and a common dermatologic skin disease that occurs on sun-exposed areas of face.


To assess the efficacy and safety of non-ablative 1,550 nm Erbium glass fractional laser therapy and compare results with those obtained with chemical peeling.


We selected 30 patients of melasma aged between 20 years and 50 years for the study. The patients were divided into two groups of 15 patients each. Group I patients were subjected to four sessions of 1,550 nm Erbium glass non-ablative fractional laser at 3 weeks interval. In group II patients, four sessions of chemical peeling with 70% glycolic acid was performed.


After 12 weeks of treatment, percentage reduction in Melasma Area and Severity Index (MASI) score was seen in 62.9% in the laser group and 58.7% in the peels group.


It was observed that 1,550 nm fractional laser is as effective as 70% glycolic acid peel in reducing MASI score in patients with melasma.


Chemical peeling; erbium glass laser; glycolic acid; hyperpigmentation; laser; melasma

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