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Annu Rev Med. 2014;65:367-83. doi: 10.1146/annurev-med-010813-102251. Epub 2013 Oct 23.

Transcatheter aortic valve replacement: game-changing innovation for patients with aortic stenosis.

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Columbia University Medical Center, New York, New York 10032; email:


Transcatheter aortic valve replacement (TAVR) is an emerging technology for the management of patients with severe aortic stenosis (AS). First reported in 2002, TAVR has made remarkable progress in the past decade with completion of major randomized clinical trials, multiple observational registries, and evolution of several new devices. This article is a brief introductory overview of the TAVR procedure, devices, trials and registries, and newer developments in the field.

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