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Chem Commun (Camb). 2013 Dec 14;49(96):11308-10. doi: 10.1039/c3cc46743k. Epub 2013 Oct 25.

A molecular logical switching beacon controlled by thiolated DNA signals.

Author information

1
Institute of Software, School of Electronics Engineering and Computer Science, Peking University, Key laboratory of High Confidence Software Technologies, Ministry of Education, Beijing, China. zhangcheng369@pku.edu.cn jxu@pku.edu.cn.

Abstract

A logical switching MB is established, with an "ON/OFF" switching function. In this study, thiolated DNA can participate as a switching controller to regulate the fluorescent increments of other DNA input signals. Assisted by gold nanoparticles and DNA branch migration, one and two-switch systems have been achieved.

PMID:
24158378
DOI:
10.1039/c3cc46743k
[Indexed for MEDLINE]

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